• Miami at New England (- 6): New England
  • Minnesota at Detroit (- 4): Detroit
  • Cincinnati at Baltimore (- 10): Cincinnati
  • Tampa Bay at New Orleans (- 7.5): Tampa Bay
  • Buffalo at New York Jets (- 3): Buffalo
  • Pittsburgh at Cleveland (+ 6): Pittsburgh
  • Oakland at Kansas City (- 4): Oakland
  • Carolina at Atlanta (- 14.5): Carolina
  • Chicago at Green Bay (- 10): Chicago
  • Arizona at San Francisco (- 6): San Francisco
  • San Diego at Denver (+ 4): Denver
  • Tennessee at Indianapolis (- 10): Indianapolis
  • Dallas at Philadelphia (- 1.5): Dallas
  • Jacksonville at Houston (- 4): Houston
  • New York Giants at Washington (+ 4.5): New York Giants
  • St. Louis at Seattle (+ 3): St. Louis