• Jacksonville at Kansas City (-9 1/2): Kansas City
  • Philadelphia at Tennessee (-3): Tennessee
  • Buffalo at Baltimore (- 14): Baltimore
  • Cleveland at New Orleans (- 14): New Orleans
  • Washington at Chicago (- 3): Chicago
  • Cincinnati at Atlanta (-3 1/2): Cincinnati
  • Pittsburgh at Miami (+3): Pittsburgh
  • San Francisco at Carolina (- 3): Carolina
  • St. Louis at Tampa Bay (- 3): St. Louis
  • Arizona at Seattle (- 7): Arizona
  • New England at San Diego (- 3): New England
  • Oakland at Denver (- 7 1/2): Denver
  • Minnesota at Green Bay (-3): Minnesota
  • New York Giants at Dallas (-3 1/2): New York Giants