• Seattle at Chicago (-6): Chicago
  • Miami at Green Bay (-3 1/2): Green Bay
  • Detroit at New York Giants (-10): New York Giants
  • San Diego at St. Louis (-8 1/2): San Diego
  • Baltimore at New England (-3): New England
  • Atlanta at Philadelphia (-2): Philadelphia
  • Kansas City at Houston (-4 1/2): Kansas City
  • Cleveland at Pittsburgh (-14): Pittsburgh
  • New Orleans at Tampa Bay (-5 1/2): Tampa Bay
  • Oakland at San Francisco (-7): Oakland
  • New York Jets at Denver (-3 1/2): Denver
  • Dallas at Minnesota (-1 1/2): Minnesota
  • Indianapolis at Washington (-3): Washington
  • Tennessee at Jacksonville (-3): Tennessee